11-Hydroxy-THC vs Delta-9: Comparing Differences, Benefits, & Effects

11 hydroxy thc vs delta 9

11-Hydroxy-THC vs Delta-9: Comparing Differences, Benefits, & Effects

Last updated on April 27th, 2023

When it comes to cannabis, there’s no denying that THC is the star of the show. But not all forms of THC are created equal. 11-Hydroxy-THC and Delta-9 are two main forms of THC that have distinct differences, benefits, and effects. In this article, we will explore the 11-Hydroxy-THC Vs Delta 9 debate, discussing their differences, benefits, and effects when consumed.

What Is 11-Hydroxy-THC?

Have you ever wondered why edibles tend to provide more intense effects than smoking or vaping cannabis? It all comes down to 11-Hydroxy-THC. 11-hydroxy-THC is the active metabolite of Delta 9 THC, one of the main psychoactive compounds in cannabis. This THC chemical compound is created through a process known as first-pass metabolism when Delta 9 THC passes through the liver and gets converted into 11-Hydoxy-THC. This compound then binds to endocannabinoid receptors, just like Delta 9 THC, to create its effects.

Interestingly enough, 11-Hydroxy-THC is not found within the cannabis plant itself. It is only created when Delta 9 THC passes through the liver, which explains why a THC edible provides far more intense effects than other forms of ingestion.

What Is Delta-9 THC?

Delta-9 THC is one of the main psychoactive compounds found in cannabis. It binds to endocannabinoid receptors throughout the body and creates a variety of effects, including relaxation, increased appetite, and pain relief. Delta 9 THC is also known for providing feelings of euphoria and mental clarity when consumed in moderate doses.

Unlike 11-hydroxy-THC, this THC cannabinoid is a naturally occurring compound and does not require conversion through the liver to become active. This means that it can be consumed in a variety of forms, including smoking, vaping, and edibles.

comparing 11 hydroxy thc vs delta 9 thc

Comparing 11-Hydroxy-THC vs Delta-9 THC

This section will discuss 11-Hydroxy-THC vs Delta 9 and look at how they differ when it comes to effects, benefits, and experiences:


11-hydroxy-THC is believed to be exponentially stronger than delta-9 THC and could potentially create much more intense psychoactive effects. In terms of similarity, both 11 hydroxy THC and delta 9 bind with endocannabinoid receptors in a similar way—providing relaxation for its users.

Metabolism & Absorption Rates

As stated before, 11-hydroxy-THC is only created when delta 9 THC passes through the liver, which is why it often comes in much higher concentrations in edibles than in other forms of cannabis consumption. Delta 9, on the other hand, does not require first-pass metabolism to become active and, as such, can be consumed without having to undergo metabolic processes. Absorption rates for 11-hydroxy-THC are also much faster than that of delta 9.


11-hydroxy-THC has also been shown to have antiemetic properties, meaning that it can help reduce nausea and vomiting in some cases. On the other hand, Delta 9 THC is well-known for providing feelings of relaxation and mental clarity when consumed in moderate doses. When it comes to the recreational aspects of cannabis, 11 hydroxy THC is often preferred due to its stronger effects and ability to provide a more intense high.

Duration Of Effects

Duration of effects is another important distinction 11-hydroxy-THC has from Delta 9 THC. 11-hydroxy THC tends to have a much longer duration of effects compared to Delta 9, usually lasting between 7 and 8 hours. Delta 9 THC, on the other hand, tends to have a longer duration of effects that can last for up to 4 or 5 hours. The duration of effects is influenced by a variety of factors, including the user’s tolerance, how much cannabis was consumed, and metabolism, as discussed above.


11-hydroxy-THC is much more potent than Delta 9 THC. 11-hydroxy THC has been shown to produce effects stronger than Delta 9, which could potentially result in a longer, more intense high for users. As a matter of fact, a 2020 study published in the Progress in Neuro-Psychopharmacology & Biological Psychiatry journal discovered that 11 hydroxy THC was significantly stronger than Delta 9, with the potential of being up to 7 times more potent.      

11-Hydroxy-THC vs Delta 9 THC Safety

Both these two forms of THC can produce unwanted side effects when consumed in incorrect doses. Below, we discuss the potential side effects of 11-hydroxy THC and Delta 9 THC.

Paranoia: 11-hydroxy THC can cause paranoia and anxiety when consumed at high doses, while Delta 9 THC is more likely to produce feelings of relaxation and mental clarity.

Dry Mouth: Dry mouth is a common side effect of consuming cannabis gummies and edibles. Ensure you have a cold beverage in hand before consuming your edibles.

Sleepiness: 11-hydroxy THC can induce drowsiness, while Delta 9 THC cannabinoid is more likely to produce an energetic high at lower doses.

Impaired Motor Coordination: 11-hydroxy THC can cause impaired motor coordination and balance, while Delta 9 THC cannabinoid has been known to produce mild effects in this regard.

Legal Considerations

Even though Delta 9 THC is federally prohibited in all U.S. states, it can be legally grown thanks to the Farm Bill of 2018’s provision. According to this bill, any plants containing less than .03 percent of this compound with dry weight volume are considered industrial hemp and thus may be lawfully cultivated.

States Where Hemp Delta-9 is Legal

Certain states are more lenient when it comes to cannabinoids, allowing the use of Delta 8, Delta 9, and CBD as long as they do not exceed 0.3 percent mandated by federal law. Below, we list a few states where hemp Delta 9 is legal.

  • Alabama
  • Connecticut and Michigan
  • Florida
  • Georgia
  • Hawaii
  • Illinois
  • Indiana
  • Kansas
  • Maine
  • Maryland
  • Massachusetts
  • Minnesota
  • Missouri 
  • Nebraska
  • New Hampshire
  • New Jersey
  • New Mexico
  • North Carolina
  • Ohio 
  • Oklahoma
  • Oregon
  • Pennsylvania
  • South Carolina
  • South Dakota
  • Tennessee
  • Texas
  • Virginia
  • West Virginia
  • Wisconsin
  • Wyoming

The Following States have outlawed Delta 9, likely due to its origins: 

  • Alaska
  • Delaware
  • Idaho
  • Iowa
  • Montana
  • Nevada
  • New York
  • North Dakota
  • Rhode Island
  • Utah
  • Vermont
  • Washington

States who are not mentioned above are in a legal gray area. By that, we mean they have not passed any legislation explicitly outlawing or decriminalizing cannabinoids. Some of these states are currently in the process of drafting bills that would do so. Until then, we advise you to use caution and consult your local laws before consuming any type of cannabinoid.

ad banner

THC Dosage

Everyone’s internal composition is distinct, and therefore, each individual’s reaction to natural remedies, like cannabis, may differ significantly. This can be influenced by multiple factors like one’s digestion or endocannabinoid system functioning. While some might only require 4-6 mg of cannabis to achieve the desired effects, others may need much more depending on their tolerance level or past experience with using it.

We recommend starting with a low dose of THC and gradually increasing it as needed to find your ideal dosage. With 11-hydroxy THC, you want to be especially mindful of the amount you consume in order to minimize the risk of overconsumption and its associated effects.

Here is a general guideline on THC consumption:

1 to 2.5mg THC: The effects of this dosage are quite remarkable. They include improved concentration and creativity and alleviation of minor symptoms related to stress, anxiety, and pain.

2.5 to 15mg of THC: By taking this dosage, you will not only benefit from improved coordination, perception, and a sense of well-being but also experience less severe symptoms of anxiety and pain relief. Furthermore, your sleep quality should be greatly enhanced!

15 to 30mg of THC: This dosage is suitable for individuals who have previously taken medication to treat insomnia and those with greater tolerance. It may impair coordination, alertness, and perception; however, some unwanted side effects are possible for people unaccustomed to it.

30 to 50mg of THC: For those with a strong THC tolerance or low cannabinoid absorption, changes in coordination and perception will be apparent. Moreover, those who are unaccustomed to this dose may experience intense euphoria.

50 to 100mg THC: This dosage of 11-Hydroxy-THC is intended for users with a high THC tolerance and advanced levels of experience. It can be beneficial to cancer patients, those suffering from inflammatory disorders, and individuals in need of higher doses of THC. Be wary, though: this amount can impair your perception and coordination and generate adverse effects such as increased heart rate, nausea, or pain.

P.S. With edibles being so tempting, it is easy to think, “I’m not feeling anything yet,” and then eat more. This can be a recipe for disaster if you overdo it, as many have experienced in the past. To avoid this temptation, having some non-cannabis treats on hand—preferably healthy ones—can help prevent any potential discomfort from occurring.

Frequently Asked Questions

Is 11-hydroxy THC Safe?

11-hydroxy THC is generally considered safe when used responsibly and in moderation. However, consuming too much 11-hydroxy THC can lead to an uncomfortable experience, including fatigue, paranoia, and stress. As with any substance or medication, it is important to follow the recommended dosage guidelines as well as consult a doctor if you have any questions or concerns.

What is stronger, delta-9 or Delta 11?

11-hydroxy THC is much more potent than Delta 9, and many users report that 11-hydroxy THC provides a stronger effect than its Delta 9 counterpart. 11-hydroxy THC has been shown to provide longer-lasting effects and can potentially have a more intense high.

Is It Possible To Vape 11-Hydroxy THC?

No, inhaling cannabis won’t create 11-hydroxy THC, as it needs to metabolize in the digestive system first.

Does 11 Hydroxy THC Contain CBD Or CBD?

No, 11-hydroxy THC does not contain CBD or any other cannabinoids aside from THC itself.

Tips On Consuming Edibles For Maximum Effect

Below, we’ve listed five tips to help you get the most out of your edibles experience:

Start with a low dose: When consuming edibles for the first time, it is important to start with a low dose and increase gradually as needed. This will help you gauge how your body reacts to the THC and avoid any unwanted side effects.

Be patient: Edibles can take up to two hours to take effect, so it is important to be patient and not consume more before the full effects have set in.

Choose wisely: With so many different types of edibles on the market, it is important to choose wisely based on your individual preferences and needs. If you are looking for a strong high, for example, then you might want to opt for a higher THC concentration.

Stay hydrated: Dehydration can increase the effect of edibles, so it is important to stay hydrated by drinking plenty of water throughout your experience.

Buy your products from a reputable source: Be sure to purchase your edibles from a trusted source to ensure that you are getting high-quality, safe products.

Remember to always exercise caution when consuming any kind of cannabis product. If you feel uncomfortable or experience any negative side effects, stop using the product immediately and contact your doctor.


The 11-hydroxy THC vs Delta 9 debate is one that has been ongoing since the discovery of 11-hydroxy THC. 11-hydroxy THC is an active metabolite of THC that has been found to possess a higher potency than Delta 9 THC. It can provide users with a longer-lasting and potentially more intense high than its Delta 9 counterpart, and it is generally considered safe when used responsibly in moderation.

However, consuming too much 11-hydroxy THC can lead to unpleasant side effects such as paranoia, anxiety, and impaired motor coordination. Lastly, Delta 9 THC is still federally illegal in all states but may be cultivated legally due to the 2018 Farm Bill’s provision. It is important to understand the differences between the two forms of THC and how they can affect you before consuming either one.

Lost 8’s carries only the best premium products like Delta 8 products, Delta 10 products, and more. Shop online or call us at (786) 910-8412 to place your order. Have questions? Connect with us by filling out a simple form or Email us.

We have something for everyone – choose from any of the following categories that fits your vibe: 




11 hydroxy thc vs delta 9 thc infographic

Leave a Comment

Your email address will not be published. Required fields are marked *