What is 11 Hydroxy THC? Exploring the Benefits and Effects

11 hydroxy thc

What is 11 Hydroxy THC? Exploring the Benefits and Effects

Last updated on April 27th, 2023

The mind-altering effects of cannabis have been the stuff of legend for centuries. However, one of its most powerful components, 11 hydroxy THC, has until recently remained shrouded in mystery. In this article, we’ll take a closer look at what is 11 hydroxy and its far-reaching implications for those wishing to unlock the power of cannabis.

What Is 11 Hydroxy THC?

11 hydroxy THC, often referred to as 11-OH-THC, is basically the result of delta-9-THC being metabolized by the body. When you swallow a THC-infused product like an edible or a pill, it immediately begins breaking down and producing a much stronger substance. This substance is known as 11 hydroxy THC.

Reports suggest that when cannabis is consumed orally, the body’s first-pass metabolism produces a higher concentration of 11 hydroxy than if it were inhaled. This could be why ingesting cannabis edibles can seem more intense and psychoactive compared to consuming an identical dosage via inhalation.

What Can 11 Hydroxy THC Be Used For?

Well, the fact that 11 hydroxy THC is much more powerful than Delta 9 immediately suggests a wealth of potential therapeutic applications. But what are they, exactly? Let’s take a look!

11 hydroxy THC has been studied and tested for its medicinal benefits in treating a variety of conditions, including:

Anxiety And Depression

Your mental health is just as important as physical health, and 11 hydroxy has been found to be useful in treating both anxiety and depression. The calming effects of this metabolite have been proven to help relieve stress and reduce feelings of uneasiness, making it a better option for those who suffer from either one or both conditions.

Promotes Good Sleep

After a long day at work, there’s nothing better than a good night’s sleep. Quality sleep is essential to maintaining healthy cognitive and emotional functions. But what if you’re having trouble getting the rest you need? 

We’ve got some good news for you. 11 hydroxy is a powerful sedative, meaning it can help you get the restful sleep that your body needs. Once taken before bed, you can literally rest assured knowing that your body is getting the rest it deserves.

Chronic Pain Caused By Arthritis And Other Illnesses

A lot of us suffer from one form of chronic pain or another, and 11 hydroxy THC is quite effective in treating it. It eases inflammation, i.e., the swelling of muscles and joints, in turn providing relief from the pain and discomfort from various conditions.

Relief From Nausea And Vomiting

You know that feeling you get when you’re about to throw up? It’s as unpleasant of an experience as it sounds, and 11 hydroxy can help with that. Research has found that the metabolite helps suppress nausea and vomiting, making it invaluable for those suffering from chemotherapy or other medical treatments.

11 hydroxy THC is quite the champ when it comes to treating medical conditions; however, its limited availability has caused it to remain largely unknown and untapped. But, with more research and understanding of this powerful metabolite, it is sure to become the go-to for many new treatments.

benefits of 11 hydroxy thc

Benefits Of 11 Hydroxy THC

So you might be asking yourself; What benefits does 11 hydroxy have over Delta 9 anyway? Well, there are plenty! Not only is it a more effective treatment for many conditions and ailments, it also offers a few other great advantages over most THCs like Delta 8 and Delta 9. Here are some of the benefits of 11 Hydroxy THC:

Increased Potency

So you want to get the most out of your cannabis experience but don’t want to smoke a ton? 11 hydroxy THC is your answer! As previously mentioned, it is much more potent than Delta 9 and can provide a stronger and longer-lasting high.

An old study compared the effects of THC and 11 hydroxy THC by administering equivalent one-milligram doses intravenously to volunteers. The results were staggering; 11 hydroxy not only provided a more intense psychoactive experience, but it also acted quicker than THC! This groundbreaking research has opened up new doors in understanding how cannabis compounds work together and interact with our bodies.

Better Bioavailability

What is bioavailability, you might ask? In simple terms, it is the amount of a certain substance that our bodies can actually absorb and utilize. The absorption rates of other cannabis compounds have been found to be lower than 11 hydroxy. What this means is that our bodies can absorb and use more of the compound, resulting in a much more powerful experience.

Stronger Effects

The effects that come with this strain are much more potent and long-lasting than any other cannabis compound. This means that you can enjoy the soothing effects of the THC for much longer and at a stronger intensity, making it perfect for medicinal purposes or recreational use. According to various studies, on average, 11 hydroxy produces psychoactive effects approximately 4.5 times more potent than the traditional THC.

The Science Behind 11 Hydroxy THC

There is a lot of science behind 11 hydroxy THC, and understanding how it works can give you a better appreciation for this unique cannabis compound:


Put simply; pharmacokinetics is the process of how a drug enters our body and its subsequent effects. 11 hydroxy THC has an interesting pharmacokinetic profile that sets it apart from other cannabis compounds. 11 Hydroxy is produced in the body as a result of liver enzymes that convert Delta-9 into its metabolite form, which is more potent and lasts longer than regular THC. This enzyme is called CYP2C9 and is found in the liver. It is responsible for converting Delta-9 into 11 Hydroxy THC, increasing the potency of your cannabis experience.

Current Research On 11-Hydroxy THC

Seeing as this active metabolite is relatively unknown, there is still a lot of research that needs to be conducted in order to fully understand the effects and potential of 11-Hydroxy. However, what has been found is quite fascinating.

Over the years, some clinical trials have suggested that 11 hydroxy may have significantly greater psychoactive effects compared to regular delta-9.

According to a study in the Journal of Clinical Investigation, 11-OH-THC is much more effective than delta-9 at inducing feelings of euphoria and rapid heartbeat. Recent animal studies have also demonstrated 11 hydroxy THC to possess more potency than delta-9.

In particular, a 2020 study on rats published in the journal Progress in Neuro Psychopharmacology & Biological Psychiatry discovered that this particular form of cannabis was anywhere from 1.5 – 7 times stronger than its counterpart.

All of these findings suggest that 11 hydroxy could be an extremely powerful asset to those looking to experience a more intense cannabis session.

11 hydroxy thc effects

What Are The Effects Of 11-Hydroxy THC?

If there is one thing that is known about 11 hydroxy, it is that the effects are incredibly powerful. The most commonly reported 11 hydroxy effects include:

  • An Intense Feeling Of Euphoria

When we say intense, we mean it! This metabolite is known to produce some of the most powerful feelings of euphoria compared to any other cannabis compound. So if you are looking for a long-lasting and potent high, this could be the right option for you.

  • Heightened Sense Of Awareness

Another common side effect of this metabolite is an increased sense of awareness. This includes heightened senses, improved focus, and concentration, as well as a deeper understanding of things around you.

  • Quick-Onset Of Psychological Effects

Unlike other forms of cannabis, 11-hydroxy THC is known to produce its effects much faster. If you are a veteran smoker who is used to waiting a while for the effects to kick in, then this is definitely something that you need to try out.

  • Increased Appetite

This might be a bad thing for some but a good thing for others. One of the 11 hydroxy THC effects is known to produce an increased appetite, which can benefit those suffering from illnesses or wanting a good munchies experience.

11 Hydroxy THC Dosage And Administration

It is important to remember that 11 hydroxy s an incredibly potent metabolite and, therefore, should be used with caution. The effects of this compound can be felt within minutes, so it’s best to start off with a lower dosage.

Most people suggest starting out with 5mg or less in order to get the desired effects without being overwhelmed. You can then work your way up as you become more familiar with the compound and its effects.

The best way to consume 11 hydroxy is orally. Oral consumption is known to provide more intense 11 hydroxy effects than other methods, such as smoking or vaping.

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Safety And Risks Of 11-Hydroxy THC

When it comes to using any form of cannabis, safety should always be your number one concern or priority. Even though 11 hydroxy THC is considered a relatively safe compound, we have heard of some reports of people experiencing adverse effects.

Overdosing on this compound can lead to an uncomfortable and prolonged experience. It’s important to note that everyone reacts differently to this metabolite, so take caution when dosing for the first time. Additionally, it is recommended that those with existing mental health issues or pre-existing conditions should consult with their doctor prior to use.

Overall, 11 hydroxy appears to be a promising metabolite that could offer many benefits to those looking to increase their cannabis experience. However, be sure to practice caution and safety when experimenting with this compound, as it can produce some intense effects.

By being aware of the potential risks and keeping your dosage in moderation, you can enjoy an amazingly potent and unique experience.

Potential Side Effects

To get a better understanding of the 11 hydroxy THC effects, let’s go over the potential side a person might experience if they use too much:


This shouldn’t be too much of a surprise seeing as THC is a mind-altering drug. Consuming too much of this metabolite may result in extreme visual and auditory hallucinations.

Rapid Heartbeat

This is a common side effect of consuming too much cannabis and is also associated with 11 hydroxy. Those with pre-existing heart conditions should avoid using this compound as it can cause serious complications.


Paranoia is another common side effect. Those who are prone to anxiety or paranoia should use this compound in moderation and with caution, as it can worsen these pre-existing conditions.


This is another side effect associated with consuming too much 11 hydroxy. As this compound can cause a person to become drowsy, it’s important to ensure that you are in a safe place before using it and that you are not operating any heavy machinery or driving.

Dry Mouth And Red Eyes

Anyone who has ever consumed cannabis knows that a dry mouth and red eyes come with the package. However, consuming too much 11 hydroxy can result in an even more intense version of this side effect. Staying hydrated while using this compound is recommended as it can help alleviate these symptoms.

Precautions And Interactions

When using 11 hydroxy THC, it’s important to understand the potential interactions and precautions associated with this compound. Those who are pregnant or breastfeeding should avoid using this compound as it can negatively affect their baby.

For those taking medications, it’s important to understand how 11 hydroxy can potentially interact with these medications and make sure that it is safe. Below is a list of potential drugs that may interact with this metabolite:

  • Antihypertensives — such as propranolol or clonidine Antiarr
  • Anti-anxiety medications — such as Valium, Xanax, and Librium
  • Antidepressants — such as Prozac and Zoloft
  • Opioid painkillers — such as OxyContin, Vicodin, and Percocet
  • Anticonvulsants (seizure medications) — such as Tegretol, Topamax, and Lyrica
  • Blood thinners — such as Coumadin and Plavix

It’s important to speak with your doctor before using 11 hydroxy if you are taking any of these medications.

Legal Status

Is 11 hydroxy THC Legal? As per the Federal Farm Bill of 2018, 11-Hydroxy-Δ⁹-tetrahydrocannabinol is legally recognized in all states due to its delta 9 THC content being below 0.3%. This particular cannabinoid is derived from delta-9 THC; however, it still remains a distinct compound within itself.

How To Use 11-HXY Legally

Below, we’ve outlined a few ways you can use 11 hydroxy THC legally.

1. Purchase it from a reputable dispensary: Many states have legalized the recreational or medical use of cannabis, which makes it easier to purchase 11-hydroxy THC from a local dispensary.

2. Purchase online: This is the most convenient way to purchase 11 hydroxy THC, as it can be shipped directly to your door. However, make sure you are purchasing from a reputable source and that the product is legal in your state.

3. Check For A Lab Analysis: When purchasing 11 hydroxy THC, make sure to check for a lab analysis of the product. This will give you an idea of how potent it is and will also provide information about any other potentially harmful compounds in the product.

Final Thoughts On 11 Hydroxy THC

11 hydroxy THC is an incredibly powerful cannabis metabolite that has the potential to give you a much stronger and longer-lasting high compared to regular delta-9 THC or Delta 8. Although more research needs to be done in this area, the available evidence suggests that this compound can provide an intense and enjoyable experience.

It is important to start off with a low dose in order to avoid being overwhelmed by the effects. Overall, 11 hydroxy could be just what you need if you are looking for an incredibly potent cannabis experience.

Get Trusted 11 Hydroxy THC Products Online Today With Lost 8s!

Lost 8s offers a wide range of products containing 11-Hydroxy THC, so you can experience the benefits of this potent metabolite in the comfort and safety of your own home. All of our products are lab tested and made from pure, natural ingredients, so you can trust that you are getting a high-quality and safe product. 

Browse our selection of 11-hydroxy THC products today for an enjoyable cannabis experience:

Purple Punch 11 Hydroxy Gummies

Trainwreck 11 Hydroxy Gummies 

what is hydroxy thc infographic

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